OAS2 Mouse Monoclonal Antibody [Clone ID: OTI6E6]

SKU TA802772S

OAS2 mouse monoclonal antibody, clone OTI6E6 (formerly 6E6)

Product Data

• Clone Name: OTI6E6
• Application: IHC, WB
• Recommended Dilution: WB 1:2000
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 60-335 of human OAS2 (NP_002526) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 78.6 kDa
• Gene Name: 2'-5'-oligoadenylate synthetase 2
• Database Link:
  NP_002526
  P29728
• Background: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul
• Synonyms: MGC78578

Reference Data

• Protein Families: Druggable Genome