Cullin 4B (CUL4B) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1C4]

SKU TA800444AM

CUL4B mouse monoclonal antibody,clone 1C4, Biotinylated

Product Data

• Clone Name: OTI1C4
• Application: IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:100
• Reactivity: Dog, Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-300 of human CUL4B (NP_003579) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 103.8 kDa
• Gene Name: cullin 4B
• Database Link:
  NP_003579
  Q13620
• Background: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

Reference Data

• Protein Pathways: Nucleotide excision repair, Ubiquitin mediated proteolysis