APE1 (APEX1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2A4]
CAT#: TA800333BM
APEX1 mouse monoclonal antibody,clone 2A4, HRP conjugated
Conjugation: Unconjugated Biotin
USD 867.00
USD 436.00
Specifications
Product Data | |
Clone Name | OTI2A4 |
Applications | FC, IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-242 of human APEX1 (NP_001632) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 35.4 kDa |
Gene Name | apurinic/apyrimidinic endodeoxyribonuclease 1 |
Database Link | |
Background | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq] |
Synonyms | APE; APE1; APEN; APEX; APX; HAP1; REF1 |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Base excision repair |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF800333 | Carrier-free (BSA/glycerol-free) APEX1 mouse monoclonal antibody, clone OTI2A4 (formerly 2A4) |
USD 600.00 |
|
TA800333 | APEX1 mouse monoclonal antibody, clone OTI2A4 (formerly 2A4) |
USD 447.00 |
|
TA800333AM | APEX1 mouse monoclonal antibody,clone 2A4, Biotinylated |
USD 509.00 |
|
TA800333S | APEX1 mouse monoclonal antibody, clone OTI2A4 (formerly 2A4) |
USD 200.00 |
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