APE1 (APEX1) Mouse Monoclonal Antibody [Clone ID: OTI2A4]

SKU
TA800333
APEX1 mouse monoclonal antibody, clone OTI2A4 (formerly 2A4)
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    Antibodies made against full-length proteins as antigens.

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$447.00
In Stock*
Specifications
Product Data
Clone Name OTI2A4
Application FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-242 of human APEX1 (NP_001632) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 35.4 kDa
Gene Name apurinic/apyrimidinic endodeoxyribonuclease 1
Database Link
Background Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]
Synonyms APE; APE1; APEN; APEX; APX; HAP1; REF1
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Protein Pathways Base excision repair
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SKU Description Size Price
CF800333 Carrier-free (BSA/glycerol-free) APEX1 mouse monoclonal antibody, clone OTI2A4 (formerly 2A4) 100 ug
$600.00
TA800333AM APEX1 mouse monoclonal antibody,clone 2A4, Biotinylated 100 ul
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TA800333BM APEX1 mouse monoclonal antibody,clone 2A4, HRP conjugated 100 ul
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TA800333S APEX1 mouse monoclonal antibody, clone OTI2A4 (formerly 2A4) 30 ul
$200.00

Citations

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