AMH Biotinylated Rabbit Monoclonal Detection Antibody (Biotin conjugated) [Clone ID: OTIR5C11]

SKU TA700549

AMH biotinylated detection Rabbit Monoclonal antibody,clone OTIR5C11

Product Data

• Clone Name: OTIR5C11
• Application: ELISA, LMNX
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein (26-560aa) of human AMH produced in HEK293
• Buffer: PBS (pH7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
• Shipping: Blue Ice
• Predicted Protein Size: 59.17 kDa
• Gene Name: anti-Mullerian hormone
• Database Link:
  NP_000470
  P03971
• Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]
• Synonyms: MIF; MIS
• Matched ELISA Pair: TA600549

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, TGF-beta signaling pathway