IL17 (IL17A) Mouse Monoclonal Capture Antibody [Clone ID: OTI1G8]

SKU TA600556

IL-17A Capture detection mouse monoclonal antibody, clone OTI1G8

Product Data

• Clone Name: OTI1G8
• Application: ELISA, LMNX
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human IL-17A (NP_002181) produced in 293 cell.
• Buffer: PBS (PH 7.3) containing 0.05% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C.; Avoid repeat freeze/thaw cycles.
• Shipping: Blue Ice
• Predicted Protein Size: 17.5 kDa
• Gene Name: interleukin 17A
• Database Link:
  NP_002181
  Q16552
• Background: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
• Synonyms: CTLA-8; CTLA8; IL-17; IL-17A; IL17; ILA17
• Matched ELISA Pair: TA600555, TA700556

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction