Histone H2A.X (H2AFX) Rabbit Monoclonal Antibody [Clone ID: OTIR1C4]

SKU TA592843S

H2AX Rabbit monoclonal antibody,clone OTIR1C4

Product Data

• Clone Name: OTIR1C4
• Application: WB
• Recommended Dilution: WB 1:500-1:2000
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human H2AX (NP_002096). The exact sequence is proprietary.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
• Shipping: Blue Ice
• Predicted Protein Size: 15.1 kDa
• Gene Name: H2A.X variant histone
• Database Link:
  NP_002096
  P16104
• Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
• Synonyms: H2A.X; H2A/X; H2AFX

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Systemic lupus erythematosus