SOD2 Rabbit Monoclonal Antibody [Clone ID: OTIR4G8]

CAT#: TA591033

Rabbit monoclonal anti-SODM antibody for SISCAPA, clone OTIR4G8

Specifications

Product Data

• Clone Name: OTIR4G8
• Applications: SISCAPA
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SOD2 (NP_000627). The exact sequence is proprietary.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: Lot dependent; please refer to CoA along with shipment
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24.8 kDa
• Gene Name: superoxide dismutase 2
• Database Link:
  NP_000627
  Entrez Gene 20656 MouseEntrez Gene 24787 RatEntrez Gene 6648 Human
  UniProt ID P04179
• Background: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]
• Synonyms: GClnc1; IPO-B; IPOB; Mn-SOD; MNSOD; MVCD6

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Huntington's disease