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ALIX (PDCD6IP) Mouse Monoclonal Antibody [Clone ID: OTI1A4]

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SKU
TA507312S
PDCD6IP mouse monoclonal antibody, clone OTI1A4 (formerly 1A4)
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $200.00
2 Days*
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View other "ALIX or NM_013374" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1A4
Application IHC, Simple Western, WB
Recommended Dilution WB 1:4000, IHC 1:150
Simple Western 1:20–1:50
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDCD6IP(NP_037506) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 95.8 kDa
Gene Name programmed cell death 6 interacting protein
Database Link
Background This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. provided by RefSeq, Jan 2012
Synonyms AIP1; ALIX; DRIP4; HP95
Reference Data
Protein Categories Cytokines, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Endocytosis
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Other "OTI1A4" antibodies (4)
SKU Description Size Price
CF507312 Carrier-free (BSA/glycerol-free) PDCD6IP mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) 100 ug
$620.00
TA507312 PDCD6IP mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) 100 ul
$447.00
TA507312AM PDCD6IP mouse monoclonal antibody, clone OTI1A4 (formerly 1A4), Biotinylated 100 ul
$509.00
TA507312BM PDCD6IP mouse monoclonal antibody, clone OTI1A4 (formerly 1A4), HRP conjugated 100 ul
$509.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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