IL6R Mouse Monoclonal Antibody [Clone ID: OTI2F4]
$200.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2F4 |
|---|---|
| Application | ELISA (indirect), IF, IHC, WB |
| Recommended Dilution | WB 1:4000, IHC 1:150, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human IL6R(NP_000556) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 49.8 kDa |
| Gene Name | interleukin 6 receptor |
| Database Link | |
| Background | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. provided by RefSeq, May 2011 |
| Synonyms | CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ |
| Reference Data | |
| Protein Categories | CD Markers, Chemokines, Cytokines, Growth Factors, Immune system diseases, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2F4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF506859 | Carrier-free (BSA/glycerol-free) IL6R mouse monoclonal antibody, clone OTI2F4 (formerly 2F4) | 100 ug |
$620.00
|
|
| TA506859 | IL6R mouse monoclonal antibody, clone OTI2F4 (formerly 2F4) | 100 ul |
$447.00
|
|
| TA506859AM | IL6R mouse monoclonal antibody,clone 2F4, Biotinylated | 100 ul |
$509.00
|
|
| TA506859BM | IL6R mouse monoclonal antibody,clone 2F4, HRP conjugated | 100 ul |
$509.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
