Neurofilament (NEFM) Mouse Monoclonal Antibody [Clone ID: OTI1A4]

SKU TA506753

NEFM mouse monoclonal antibody, clone OTI1A4 (formerly 1A4)

Product Data

• Clone Name: OTI1A4
• Application: IF, WB
• Recommended Dilution: WB 1:1000 -1:4000, IF 1:100
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human NEFM(NP_005373) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 102.3 kDa
• Gene Name: neurofilament medium chain
• Database Link:
  NP_005373
  P07197
• Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
• Synonyms: NEF3; NF-M; NFM

Reference Data

• Protein Pathways: Amyotrophic lateral sclerosis (ALS)