PMS2 Mouse Monoclonal Antibody [Clone ID: OTI2G5]
PMS2 mouse monoclonal antibody, clone OTI2G5 (formerly 2G5)
Product Datasheet for 'TA506658'
|Applications||IF, IHC, WB|
|Recommend Dilution||WB 1:500, IHC 1:150, IF: 1:100|
|Immunogen||Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.|
|Formulation||PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from mouse ascites fluids by affinity chromatography|
|Predicted Protein Size||95.6 kDa|
|Gene Name||PMS1 homolog 2, mismatch repair system component|
|Background||This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]|
|Synonyms||HNPCC4; PMS2CL; PMSL2|
|Protein Families||Druggable Genome|
|Protein Pathways||Mismatch repair|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.