Tyrosine Hydroxylase (TH) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A12]

SKU TA506540AM

TH mouse monoclonal antibody,clone 1A12, Biotinylated

Product Data

• Clone Name: OTI1A12
• Application: IF, IHC, WB
• Recommended Dilution: WB 1:4000, IF 1:100, IHC: 1:150
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human TH(NP_000351) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 55.4 kDa
• Gene Name: tyrosine hydroxylase
• Database Link:
  NP_000351
  P07101
• Background: The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: DYT5b; DYT14; TYH

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Parkinson's disease, Tyrosine metabolism