FGFR2 Mouse Monoclonal Antibody [Clone ID: OTI5C5]
SKU
TA503137
FGFR2 mouse monoclonal antibody, clone OTI5C5 (formerly 5C5)
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TrueMAB™
Antibodies made against full-length proteins as antigens.
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Product Data | |
Clone Name | OTI5C5 |
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Application | FC, IF, IHC, WB |
Recommended Dilution | WB 1:200 - 1:1000, IHC 1:150, IF 1:100, FLOW 1:100 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human FGFR2(NP_000132) produced in HEK293T cell. |
Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | fibroblast growth factor receptor 2 |
Database Link | |
Background | The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq] |
Synonyms | BBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Secreted Protein, Transmembrane |
Protein Pathways | Endocytosis, MAPK signaling pathway, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton |
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Product Manuals |
FAQs |
SDS |
Antibody Resources |
SKU | Description | Size | Price | |
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CF503137 | Carrier-free (BSA/glycerol-free) FGFR2 mouse monoclonal antibody, clone OTI5C5 (formerly 5C5) | 100 ug |
$600.00
|
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TA503137AM | FGFR2 mouse monoclonal antibody,clone 5C5, Biotinylated | 100 ul |
$509.00
|
|
TA503137BM | FGFR2 mouse monoclonal antibody,clone 5C5, HRP conjugated | 100 ul |
$509.00
|
|
TA503137S | FGFR2 mouse monoclonal antibody, clone OTI5C5 (formerly 5C5) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.