Beclin 1 (BECN1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4A10]

SKU TA502617AM

BECN1 (Beclin 1) mouse monoclonal antibody, clone OTI4A10 (formerly 4A10), Biotinylated

Product Data

• Clone Name: OTI4A10
• Application: FC, IF, WB
• Recommended Dilution: WB 1:2000, IF 1:100, FLOW 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human BECN1 (NP_003757) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 51.7 kDa
• Gene Name: beclin 1
• Database Link:
  NP_003757
  Q14457
• Background: Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]). [supplied by OMIM, Jul 2010]
• Synonyms: ATG6; beclin1; VPS30

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Regulation of autophagy