Gephyrin (GPHN) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1C5]

SKU TA502218AM

GPHN (Gephyrin) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5), Biotinylated

Product Data

• Clone Name: OTI1C5
• Application: IF, WB
• Recommended Dilution: WB 1:2000, IF 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human GPHN (NP_065857) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 83.3 kDa
• Gene Name: gephyrin
• Database Link:
  NP_065857
  Q9NQX3
• Background: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq]
• Synonyms: GEPH; GPH; GPHRYN; HKPX1; MOCODC

Reference Data

• Protein Families: Druggable Genome