GALE Mouse Monoclonal Antibody [Clone ID: OTI1C4]
CAT#: TA502146
GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4)
Size: 30 ul
Formulation: Carrier-Free
USD 436.00
USD 867.00
Specifications
Product Data | |
Clone Name | OTI1C4 |
Applications | IHC, WB |
Recommended Dilution | WB 1:500~2000, IHC 1:150 |
Reactivities | Human, Dog, Rat, Monkey, Mouse |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human GALE (NP_000394) produced in HEK293T cell. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 38.1 kDa |
Gene Name | UDP-galactose-4-epimerase |
Database Link | |
Background | This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
Synonyms | SDR1E1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF502146 | Carrier-free (BSA/glycerol-free) GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) |
USD 600.00 |
|
TA502146AM | GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4), Biotinylated |
USD 509.00 |
|
TA502146BM | GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4), HRP conjugated |
USD 509.00 |
|
TA502146S | GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) |
USD 200.00 |
{0} Product Review(s)
Be the first one to submit a review