HIPPI (IFT57) Mouse Monoclonal Antibody [Clone ID: OTI4F6]

CAT#: TA500918

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Anti-IFT57 (HIPPI) mouse monoclonal antibody, clone OTI4F6 (formerly 4F6)



  View other "OTI4F6" antibodies (2)

USD 379.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI4F6
Applications IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human IFT57(NP_060480) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 49.1 kDa
Gene Name intraflagellar transport 57
Background Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1,leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3'present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear
Synonyms ESRRBL1; HIPPI; MHS4R2
Reference Data
Protein Families Druggable Genome
Protein Pathways Huntington's disease

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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