LOX Mouse Monoclonal Antibody [Clone ID: OTI6B7]

CAT#: TA500869

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LOX mouse monoclonal antibody, clone OTI6B7 (formerly 6B7)



  View other "OTI6B7" antibodies (4)

USD 447.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI6B7
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:50, IF 1:100, FLOW 1:100
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 46.8 kDa
Gene Name lysyl oxidase
Background The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms MGC105112
Reference Data
Protein Families Druggable Genome, Secreted Protein

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