FKBP12 (FKBP1A) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3B3]

SKU TA500557BM

FKBP1A (FKBP12) mouse monoclonal antibody, clone OTI3B3 (formerly 3B3), HRP conjugated

Product Data

• Clone Name: OTI3B3
• Application: FC, IHC, WB
• Recommended Dilution: WB: 1:200 - 1:1000, IHC 1:150, FLOW 1:100
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human FKBP1A (NP_000792) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 11.8 kDa
• Gene Name: FKBP prolyl isomerase 1A
• Database Link:
  NP_000792
  P62942
• Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq]
• Synonyms: FKBP-1A; FKBP-12; FKBP1; FKBP12; PKC12; PKCI2; PPIASE
• Note: WB application: Only overexpression results are guaranteed, not endogenous.

Reference Data

• Protein Families: Druggable Genome