LAT2 (SLC7A8) Mouse Monoclonal Antibody [Clone ID: OTI7D6]

SKU
TA500515
Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6)
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    Antibodies made against full-length proteins as antigens.

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$447.00
In Stock*
Specifications
Product Data
Clone Name OTI7D6
Application IHC, WB
Recommended Dilution WB: 1:200 - 1:1000, IHC 1:50
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human SLC7A8 expression vector
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.8 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 58.4 kDa
Gene Name solute carrier family 7 member 8
Database Link
Background Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
Synonyms LAT2; LPI-PC1
Reference Data
Protein Families Druggable Genome, Transmembrane
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SKU Description Size Price
CF500515 Carrier-free (BSA/glycerol-free) SLC7A8 mouse monoclonal antibody, clone OTI7D6 (formerly 7D6) 100 ug
$600.00
TA500515AM Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6), Biotinylated 100 ul
$509.00
TA500515BM Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6), HRP conjugated 100 ul
$509.00
TA500515S Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6) 30 ul
$200.00

Citations

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