LAT2 (SLC7A8) Mouse Monoclonal Antibody [Clone ID: OTI7D6]
SKU
TA500515
Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6)
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TrueMAB™
Antibodies made against full-length proteins as antigens.
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Product Data | |
Clone Name | OTI7D6 |
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Application | IHC, WB |
Recommended Dilution | WB: 1:200 - 1:1000, IHC 1:50 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full-length protein expressed in 293T cell transfected with human SLC7A8 expression vector |
Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.8 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 58.4 kDa |
Gene Name | solute carrier family 7 member 8 |
Database Link | |
Background | Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney. |
Synonyms | LAT2; LPI-PC1 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
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Antibody Resources |
SKU | Description | Size | Price | |
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CF500515 | Carrier-free (BSA/glycerol-free) SLC7A8 mouse monoclonal antibody, clone OTI7D6 (formerly 7D6) | 100 ug |
$600.00
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TA500515AM | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6), Biotinylated | 100 ul |
$509.00
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TA500515BM | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6), HRP conjugated | 100 ul |
$509.00
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TA500515S | Anti-SLC7A8 (LAT2) mouse monoclonal antibody, clone OTI7D6 (formerly 7D6) | 30 ul |
$200.00
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.