Lamin B1 (LMNB1) Rabbit Monoclonal Antibody
| Product Data | |
| Application | ICC/IF, IHC, IP, WB |
|---|---|
| Recommended Dilution | WB 1:3000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human Lamin B1 |
| Specificity | Lamin B1 Antibody detects endogenous levels of total Lamin B1 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 70kDa |
| Gene Name | lamin B1 |
| Database Link | |
| Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. |
| Synonyms | ADLD; Lamin B1; LMN; LMN2; LMNB |
| Reference Data | |
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