Chk2 (CHEK2) Rabbit Monoclonal Antibody
| Product Data | |
| Application | IP, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 IP 1:50 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human Phospho-Chk2 (T68) |
| Specificity | Phospho-Chk2 (T68) Antibody detects endogenous levels of total Phospho-Chk2 (T68) |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 65kDa |
| Gene Name | checkpoint kinase 2 |
| Database Link | |
| Background | These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. |
| Synonyms | Cds1; CHEK2; CHK2; Chk2; EC 2.7.11.1; kinase Chk2; RAD53 |
| Reference Data | |
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