M6PR Rabbit Monoclonal Antibody
| Product Data | |
| Application | FC, ICC/IF, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human M6PR |
| Specificity | M6PR Antibody detects endogenous levels of total M6PR |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 42kDa |
| Gene Name | mannose-6-phosphate receptor, cation dependent |
| Database Link | |
| Background | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. |
| Synonyms | CD MPR; M6pr; Man6PR; MPR46; MPRD; SMPR |
| Reference Data | |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.