CARD11 Rabbit Monoclonal Antibody
| Product Data | |
| Application | ICC/IF, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human CARD11 |
| Specificity | CARD11 Antibody detects endogenous levels of total CARD11 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -23°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 133kDa |
| Gene Name | caspase recruitment domain family member 11 |
| Database Link | |
| Background | Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. |
| Synonyms | BIMP3; CARD11; CARMA1; Carma 1 |
| Reference Data | |
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