Presenilin 1 (PSEN1) Rabbit Monoclonal Antibody
| Product Data | |
| Application | FC, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 FC1:10 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human Presenilin 1 |
| Specificity | Presenilin 1 Antibody detects endogenous levels of total Presenilin 1 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -24°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 28kDa |
| Gene Name | presenilin 1 |
| Database Link | |
| Background | Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. |
| Synonyms | AD3; Ad3h; FAD; Protein S182; PS1-CTF12; PSEN1; PSNL1; S182 |
| Reference Data | |
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