Axin 2 (AXIN2) Rabbit Monoclonal Antibody
| Product Data | |
| Application | ICC/IF, IHC, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human Axin2 |
| Specificity | Axin2 Antibody detects endogenous levels of total Axin2 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 94kDa |
| Gene Name | axin 2 |
| Database Link | |
| Background | Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin. |
| Synonyms | Axil; Axin2; Axin like protein; Axis inhibition protein 2; Conductin |
| Reference Data | |
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