FKBP12 (FKBP1A) Rabbit Monoclonal Antibody
| Product Data | |
| Application | ICC/IF, WB |
|---|---|
| Recommended Dilution | WB 1:1000~1:5000 ICC/IF 1:50~1:200 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human FKBP12 |
| Specificity | FKBP12 Antibody detects endogenous levels of total FKBP12 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -23°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 12kDa |
| Gene Name | FK506 binding protein 1A |
| Database Link | |
| Background | May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| Synonyms | FKBP1; FKBP 1A; fkbp1a; FKBP 12; FKBP12 Exip3; FKBP12C; Immunophilin FKBP12; PKC12; PPIase FKBP1A; Rotamase |
| Reference Data | |
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