Doublecortin (DCX) Rabbit Monoclonal Antibody
| Product Data | |
| Application | FC, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 FC 1:50~1:200 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human DCX |
| Specificity | DCX Antibody detects endogenous levels of total DCX |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -21°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 45kDa |
| Gene Name | doublecortin |
| Database Link | |
| Background | Mutations in Doublecortin cause Lissencephaly (smooth brain), a neuronal migration disorder characterized by epilepsy and mental retardation. Doublecortin is a microtubule associated protein that stabilizes and bundles microtubules. A conserved doublecortin domain mediates the interaction with microtubules, and interestingly most missense mutations cluster in this domain. |
| Synonyms | DBCN; DC; DCX; doublecortin; Doublin; LISX; SCLH; XLIS |
| Reference Data | |
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