STAT3 Rabbit Monoclonal Antibody
Product Data | |
Application | ICC/IF, IHC, IP, WB |
---|---|
Recommended Dilution | WB 1:5000~1:10000 IHC 1:50~1:100 ICC/IF 1:50~1:000 IP 1:30 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | A synthesized peptide derived from human STAT3 |
Specificity | Phospho-STAT3 (Y705) Antibody detects endogenous levels of total Phospho-STAT3 (Y705) |
Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity-chromatography |
Conjugation | Unconjugated |
Storage | Store at +4°C short term. Store at -24°C long term. Avoid freeze / thaw cycle. |
Shipping | Blue Ice |
Predicted Protein Size | 88kDa |
Gene Name | signal transducer and activator of transcription 3 |
Database Link | |
Background | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. |
Synonyms | Acute-phase response factor; APRF; HIES; Stat3 |
Reference Data |
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