AKT1 Rabbit Monoclonal Antibody
| Product Data | |
| Application | IP, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:1000 IP 1:50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human AKT1 |
| Specificity | Phospho-AKT1 (S124) Antibody detects endogenous levels of Phospho-AKT1 (S124) |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -21°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 60kDa |
| Gene Name | AKT serine/threonine kinase 1 |
| Database Link | |
| Background | Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473. |
| Synonyms | AKT 1; PKB; PKB-ALPHA; PRKBA; Protein kinase B; Protein Kinase B Alpha; Proto-oncogene c-Akt; RAC Alpha |
| Reference Data | |
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