DKK1 Rabbit Monoclonal Antibody
| Product Data | |
| Application | FC, ICC/IF, IHC, WB |
|---|---|
| Recommended Dilution | WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50 |
| Reactivity | Human, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human DKK1 |
| Specificity | DKK1 Antibody detects endogenous levels of DKK1 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -23°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 38kDa |
| Gene Name | dickkopf WNT signaling pathway inhibitor 1 |
| Database Link | |
| Background | DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
| Synonyms | Dickkopf-1; Dickkopf-related protein 1; Dickkopf homolog 1; DKK-1; hDkk-1; SK |
| Reference Data | |
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