RALBP1 Rabbit Monoclonal Antibody
| Product Data | |
| Application | FC, IHC, WB |
|---|---|
| Recommended Dilution | WB 1:5000~1:10000 IHC 1:50~1:200 FC 1:50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human RALBP1 |
| Specificity | RALBP1 Antibody detects endogenous levels of RALBP1 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 95kDa |
| Gene Name | ralA binding protein 1 |
| Database Link | |
| Background | RalBP1 interacts with RalA and the endocytosis protein REPS2 (POB1) through its carboxy-terminal Ral binding domain. RalBP1 has an intrinsic GTPase activating function and interacts with Cdc42 through its centrally located Rho-GAP domain. A protein complex containing RalBP1/POB1/RalA regulates endocytosis of membrane receptors. RalBP1 also functions as a non-ABC transporter that catalyzes the ATP-dependent transport of numerous xenobiotics, including glutathione conjugates and some chemotherapeutic agents. |
| Synonyms | RALBP1; RIP1; RLIP1; RLIP76 |
| Reference Data | |
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