FGFR1 Rabbit Monoclonal Antibody
| Product Data | |
| Application | ICC/IF, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:1000 ICC/IF 1:50~1:200 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human FGFR1 |
| Specificity | FGFR1 Antibody detects endogenous levels of FGFR1 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 140kDa |
| Gene Name | fibroblast growth factor receptor 1 |
| Database Link | |
| Background | Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766. |
| Synonyms | BFGFR; CD331; CEK; FGFBR; FGF Receptor 1; FLG; FLJ99988; FLT2; HBGFR; KAL2; N-SAM; OGD |
| Reference Data | |
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