EGFR Rabbit Monoclonal Antibody
| Product Data | |
| Application | ICC/IF, IP, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human Phospho-EGFR (Y1086) |
| Specificity | Phospho-EGFR (Y1086) Antibody detects endogenous levels of Phospho-EGFR (Y1086) |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 150kDa |
| Gene Name | epidermal growth factor receptor |
| Database Link | |
| Background | The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysosomal degradation. Phospho-EGF Receptor (Tyr1086) Antibody is directed against a previously unpublished EGF receptor phosphorylation site at Tyr1086, Phosphorlation of EGF receptor at Tyr1086 was observed in select carcinoma cell lines and in tumors. |
| Synonyms | EC 2.7.10.1; Epidermal growth factor receptor precursor; ERBB1; kinase EGFR; Receptor protein-tyrosine kinase ErbB-1 |
| Reference Data | |
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