p53 (TP53) Rabbit Monoclonal Antibody
| Product Data | |
| Application | ICC/IF, WB |
|---|---|
| Recommended Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human Phospho-p53 (S33) |
| Specificity | Phospho-p53 (S33) Antibody detects endogenous levels of total Phospho-p53 (S33) |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -21°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 53kDa |
| Gene Name | tumor protein p53 |
| Database Link | |
| Background | Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. |
| Synonyms | Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53 |
| Reference Data | |
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