PARP1 Rabbit Monoclonal Antibody

SKU
TA422205
Cleaved PARP Antibody
$480.00
4 Weeks*
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB 1:500~1:2000 IHC 1:50~1:100
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen A synthesized peptide derived from human Cleaved PARP
Specificity This antibody is specific for the p25 cleaved form of human PARP.
Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration lot specific
Purification Affinity-chromatography
Conjugation Unconjugated
Storage Store at +4°C short term. Store at -21°C long term. Avoid freeze / thaw cycle.
Shipping Blue Ice
Predicted Protein Size 25kDa
Gene Name poly(ADP-ribose) polymerase 1
Database Link
Background Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Synonyms ADPRT; ADPRT1; pADPRT-1; PARP; PARP-1; PPOL
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.