LRP2 Rabbit Monoclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | WB 1:500~1:2000 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | A synthesized peptide derived from human Lrp2 / Megalin |
Specificity | Lrp2 / Megalin Antibody detects endogenous levels of total Lrp2 / Megalin |
Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity-chromatography |
Conjugation | Unconjugated |
Storage | Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle. |
Shipping | Blue Ice |
Predicted Protein Size | 280kDa |
Gene Name | LDL receptor related protein 2 |
Database Link | |
Background | LRP2, also named as gp330 and Megalin, belongs to the LDLR family. It acts together with cubilin to mediate HDL endocytosis. LRP2 may participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release. Defects in LRP2 are the cause of Donnai-Barrow syndrome (DBS). The antibody is specific to LRP2. |
Synonyms | DBS; Glycoprotein 330; gp330; Low-density lipoprotein receptor-related protein 2; LRP-2; LRP2; Megalin |
Reference Data |
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