Cd3e Hamster Monoclonal Antibody [Clone ID: 145-2C11]

SKU TA420133

Cd3e hamster monoclonal antibody, clone 145-2C11, ALEXA FLUOR® 488,ALEXA FLUOR® 647,Amethyst Blue,Amethyst Orange,Biotin,FITC,Pacific Blue®,Purified,RPE,RPE-CY5,RPE-CY5.5,RPE-CY7

Product Data

• Clone Name: 145-2C11
• Application: FC, IF, IHC, IP, WB
• Antibody Host: Hamster
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: H-2K^b - specific mouse cytotoxic T lymphocyte clone BM10-37.
• Specificity: CD3
• Buffer: Phosphate buffered saline containing 0.09% Sodium Azide (NaN3); Label: ALEXA FLUOR® 488,ALEXA FLUOR® 647,Amethyst Blue,Amethyst Orange,Biotin,FITC,Pacific Blue®,Purified,RPE,RPE-CY5,RPE-CY5.5,RPE-CY7; State: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant Purified IgG - liquid
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: +4°C, -20°C if preferred
• Stability: Shelf life: one year from despatch.
• Shipping: Ambient
• Gene Name: CD3 antigen, epsilon polypeptide
• Database Link:
  P22646
• Background: Hamster anti Mouse CD3 antibody, clone 145-2C11 detects CD3 epsilon (CD3ε), a ~20 kDa transmembrane protein also known as CD3 or T3. CD3ε is a member of the CD3 complex which consists of four subunits, gamma, delta, epsilon and zeta, and these are associated to the T cell receptor (TCR). TCR plays a critical role in T cell development and function, and is responsible for ligand recognition. It interacts non-covalently with the CD3 dimers delta/epsilon, gamma/epsilon and zeta/zeta which transduce signals from the TCR into the cell.CD3ε is primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation.Hamster anti Mouse CD3 antibody, clone 145-2C11 is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vitro T cell depletions.
• Synonyms: CD3-epsilon; FLJ18683; T3E; TCRE

Reference Data