HES1 Mouse Monoclonal Antibody [Clone ID: OTI4H1]

CAT#: TA400012

Anti-HES1 mouse mAb, clone OTI4H1, Biotinylated

Product Images

HEK293T cells were transfected with pCMV6-ENTRY control (Lane 1) or pCMV6-ENTRY HES1 (Lane 2) plasmids for 48 hrs. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1-biotin and Streptavidin-HRP.

Specifications

Product Data

• Clone Name: OTI4H1
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant protein expressed in E.coli corresponding to amino acids 1-280 of human HES1
• Formulation: PBS (pH7.4) containing 50% glycerol, 0.1% BSA and 0.02% NaN3
• Concentration: 0.5 mg/ml
• Purification: Purified from cell culture supernatant by affinity chromatography
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29.4 kDa
• Gene Name: hes family bHLH transcription factor 1
• Database Link:
  NP_005515
  Entrez Gene 3280 Human
  UniProt ID Q14469
• Background: This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
• Synonyms: bHLHb39; HES-1; HHL; HRY

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young, Notch signaling pathway