Ku70 (XRCC6) Rabbit Polyclonal Antibody

SKU TA392942

Ku-70 (phospho-S5) polyclonal antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500~1:1000
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from human Ku-70 around the phosphorylation site of S5.
• Specificity: Ku-70 (phospho-S5) polyclonal antibody detects endogenous levels of Ku-70 protein around the phosphorylation site of S5.
• Buffer: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Shipping: Blue Ice
• Predicted Protein Size: ~ 70 kDa
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 6
• Database Link:
  P12956
• Background: The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 (or p86), which is also known by the synonym Ku-80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation.
• Synonyms: 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; Chinese hamster cells 6; CTC75; CTCBF; CTC box-binding factor 75 kDa subunit; DNA repair protein XRCC6; G22P1; Ku70; Lupus Ku autoantigen protein p70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in; X-ray repair cross-complementing protein 6; XRCC6
• Note: For research use only, not for use in diagnostic procedure.

Reference Data