Rabbit Polyclonal Antibody

SKU TA392880

Adducin α/β (phospho-S726/713) polyclonal antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500~1:1000 IHC: 1:50~1:200
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic phosphopeptide derived from human Adducin α around the phosphorylation site of Serine 726.
• Specificity: p-Adducin α/β (S726/713) polyclonal antibody detects endogenous levels of Adducin α protein only when phosphorylated at Ser726 and Adducin β protein only when phosphorylated at Ser713.
• Buffer: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Shipping: Blue Ice
• Predicted Protein Size: ~ 81 kDa
• Database Link:
  P35611/P35612
• Background: Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
• Synonyms: ADD1; ADD2; ADDA; ADDB; Adducin-1; Adducin-α; Adducin-β; Adducin1; Adducin β; Alpha-adducin; Beta-adducin; Erythrocyte adducin subunit alpha; Erythrocyte adducin subunit beta; α-Adducin; α Adducin; β-Adducin; β Adducin
• Note: For research use only, not for use in diagnostic procedure.

Reference Data