SFRS15 (SCAF4) Rabbit Polyclonal Antibody
Product Data | |
Application | WB |
---|---|
Recommended Dilution | WB: 1:500~1:1000 IHC: 1:50~1:200 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 611-660 of Human SFRS15. |
Specificity | SFRS15 (V641) polyclonal antibody detects endogenous levels of SFRS15 protein. |
Buffer | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Concentration | 1mg/ml |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Stability | 1 year |
Shipping | Blue Ice |
Predicted Protein Size | ~ 126 kDa |
Gene Name | SR-related CTD associated factor 4 |
Database Link | |
Background | The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing. |
Synonyms | CTD-binding SR-like protein RA4; KIAA1172; SCAF4; SFRS15; Splicing factor, arginine/serine-rich 15; SR-related and CTD-associated factor 4 |
Note | For research use only, not for use in diagnostic procedure. |
Reference Data |
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