SLC16A13 Rabbit Polyclonal Antibody

SKU
TA392836
SLC16A13 (L423) polyclonal antibody
$340.00
7 Weeks*
Specifications
Product Data
Application WB
Recommended Dilution WB: 1:500~1:1000
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 389-442 of Human SLC16A13.
Specificity SLC16A13 (L423) polyclonal antibody detects endogenous levels of SLC16A13 protein.
Buffer Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Stability 1 year
Shipping Blue Ice
Predicted Protein Size ~ 40 kDa
Gene Name solute carrier family 16 member 13
Database Link
Background Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.
Synonyms MCT 13; MCT13; Monocarboxylate transporter 13; SLC16A13; Solute carrier family 16 member 13
Note For research use only, not for use in diagnostic procedure.
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.