Lysophospholipase 1 (LYPLA1) Rabbit Polyclonal Antibody

SKU TA392827

LYPLA1 (K90) polyclonal antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500~1:1000 IHC: 1:50~1:200
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 61-110 of Human LYPLA1.
• Specificity: LYPLA1 (K90) polyclonal antibody detects endogenous levels of LYPLA1 protein.
• Buffer: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Shipping: Blue Ice
• Predicted Protein Size: ~ 25 kDa
• Gene Name: lysophospholipase I
• Database Link:
  O75608
• Background: Acyl-protein thioesterase 1 (APT1, Lysophospholipase 1) is a member of a family of critical enzymes, lysophospholipases, that act on biological membranes to regulate the multifunctional lysophospholipids. APT1 hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. The role of APT1 in regulating lysophospholipids is important because increased levels of lysophospholipids are detected in a variety of diseases, including atherosclerosis and hyperlipidemia. Regulated expression of acyl-protein thioesterase by PKC has been suggested to have important implications for signal transduction processes.
• Synonyms: Acyl-protein thioesterase 1; APT-1; APT1; hAPT1; LPL-I; LPL1; LYPLA1; Lysophospholipase 1; Lysophospholipase I; LysoPLA I
• Note: For research use only, not for use in diagnostic procedure.

Reference Data