Synphilin 1 (SNCAIP) Rabbit Polyclonal Antibody

SKU TA392818

Synphilin-1 (R846) polyclonal antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500~1:1000 IHC: 1:50~1:200
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 815-867 of Human Synphilin-1.
• Specificity: Synphilin-1 (R846) polyclonal antibody detects endogenous levels of Synphilin-1 protein.
• Buffer: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Shipping: Blue Ice
• Predicted Protein Size: ~ 100 kDa
• Gene Name: synuclein alpha interacting protein
• Database Link:
  Q9Y6H5
• Background: Synphilin-1 (α-synuclein interacting protein, SNCAIP) is a 919 amino acid protein that associates with α synuclein and promotes the formation of cytosolic inclusions in neuronal cells. The synuclein family members, including α-synuclein and β-synuclein, are predominantly expressed in the brain, where they influence synaptic regulation and neuronal plasticity. Synphilin-1 contains modular protein domains, such as ankyrin-like repeats and a coiled-coil domain.While both α-synuclein and synphilin-1 are coexpressed in Lewy bodies of patients with Parkinson’s disease, only mutations in the gene for α-synuclein have been determined to confer pathogenicity.
• Synonyms: Alpha-synuclein-interacting protein; SNCAIP; Sph1; Synphilin-1
• Note: For research use only, not for use in diagnostic procedure.

Reference Data