Integrin alpha 5 (ITGA5) Rabbit Polyclonal Antibody

SKU TA392424

Integrin α5 (CD49e) polyclonal antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:2000~1:5000
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human Integrin α5.
• Specificity: Integrin α5 polyclonal antibody detects endogenous levels of Integrin α5 protein.
• Buffer: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Shipping: Blue Ice
• Predicted Protein Size: ~ 130 kDa
• Gene Name: integrin subunit alpha 5
• Database Link:
  P08648
• Background: Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling). Integrin α5/β1 is involved in multiple biological processes including embryonic development, angiogenesis and tumor metastasis. By interaction with its fibronectin ligand, α5/β1 transduces signals that regulate cell adhesion, migration, matrix assembly and cytoskeletal organization.
• Synonyms: CD49 antigen-like family member E; CD49e; Fibronectin receptor subunit alpha; FNRA; Integrin alpha-5; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; Integrin alpha-F; ITGA5; VLA-5
• Note: For research use only, not for use in diagnostic procedure.

Reference Data