Itgb7 Rabbit Monoclonal Antibody [Clone ID: FIB504]

SKU TA386024

Recombinant Anti-Integrin beta-7 (Clone FIB504)

Product Data

• Clone Name: FIB504
• Application: Bl, FC, IF
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: FIB504 was prepared by immunizing rats with TK1 cells.
• Specificity: FIB504 recognizes an epitope on intergin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.; ; FIB504 can be used for IF, FC and can block TKI cell aggregation and beta-7 intergrin-mediated cell adhesion.
• Buffer: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Shipping: Blue Ice
• Gene Name: integrin beta 7
• Database Link:
  P26011
• Synonyms: ITGB7
• Note: This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Reference Data