TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: CDP 571 (Humicade)]

SKU TA385964

Recombinant Anti-TNF alpha (Clone CDP 571 (Humicade))

Product Data

• Clone Name: CDP 571 (Humicade)
• Application: ELISA
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Human TNF-alpha
• Specificity: The antibody binds to human TNF-alpha with a Kd of 0.087 nM.; ; The antibody binds specifically to TNF-alpha, a pro-inflammatory cytokine which stimulates release of other cytiokines e.g. IL-1, IL-6 and GM-CSF as well as secretion of ICAM-1 and VCAM-1 from endothelial cells. It stimulates acute phase responses and acts as a chemoattractant for NK cells and monocytes/macrophages. The antibody reached Phase II clinical trials with Celltech, UCB.
• Buffer: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Shipping: Blue Ice
• Gene Name: tumor necrosis factor
• Database Link:
  P01375
• Synonyms: Cachectin; DIF; TNF-a; TNF-alpha; TNFA; TNFSF2
• Note: NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Reference Data