Cytokeratin 17 (KRT17) Mouse Monoclonal Antibody [Clone ID: 8C6-4H2-5C1]
| Product Data | |
| Clone Name | 8C6-4H2-5C1 |
|---|---|
| Application | IF, IHC, IP, WB |
| Recommended Dilution | WB: 1/1000 IP: 1/200 IF: 1/200 IHC: 1/50-300 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Synthetic Peptide of CK17 |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3. |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | Observed MW (kDa):48 |
| Gene Name | keratin 17 |
| Database Link | |
| Background | Swiss-Prot Acc.Q04695.Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair . Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state . Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway . Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial |
| Synonyms | 39.1; CK-17; Cytokeratin-17; K17; Keratin-17; PC; PC2; PCHC1 |
| Reference Data | |
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